Just stop that shit, people. It'll kill you.Harvesting the genetic data from the participants, researchers looked at the activity of nearly 600 genes, all of which are related to controlling and mounting immune responses. Comparing smokers’ genetic information to that of non-users, the team found that the activity of 53 genes was dialed down in smokers collectively. Comparing e-cig users to smokers and non-users revealed the same dampened activity for those 53 genes but also 305 others—a total of 358 immune genes were muted in e-cig users’ noses.
In follow-up lab studies, Jaspers and colleagues tested e-cig liquid on immune cells from healthy volunteers. Specifically, the researchers collected immune cells, such as neutrophils and macrophages, that are responsible in part for swallowing up invading bacteria. When the cells were put into diluted solutions of different e-cigarette liquids, the cells weren’t as good at sucking in the microbes. The data, while preliminary, suggests that immune cells in e-cig users may be unable to prevent bacterial breaches, thus opening the gates to infection.
The researchers also looked at the gene-altering effects of different flavors of e-cigarettes on the cells in the delicate lining of the respiratory tract.
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The point is driven home with one of the flavors, the butter-mimicking diacetyl. This flavor has been found in some e-cig flavorings, but it's known to cause bronchiolitis obliterans, a severe disease caused by scar tissue and inflammation built up deep in the lungs. The link was discovered years ago in food manufacturing, particularly microwave popcorn factory employees who developed “popcorn worker’s lung.”
http://arstechnica.com/science/2016/02/ ... cigs-dont/