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How do injections work?
Posted: Sun May 15, 2005 9:48 am
by SplishSplash
When I had my wisdom teeth pulled, they gave me an injection into a vein in my left arm. Seconds later I was unconscious.
How does that work? No way the stuff could have made it's way all the way to my brain in 2 or 3 seconds?

Posted: Sun May 15, 2005 9:52 am
by Deji
Why unconscious anyway? When they pulled my tooth, they only did a local anaesthesia.
Posted: Sun May 15, 2005 9:58 am
by Zyte -_-
yes me too, one in my tongue, one by my jaw.
Posted: Sun May 15, 2005 10:01 am
by SplishSplash
Deji wrote:Why unconscious anyway? When they pulled my tooth, they only did a local anaesthesia.
They gave me the choice. I chose not to experience the whole ordeal, and I was pretty happy about that decision later on.
Also, it was 4 teeth, not just one.
Posted: Sun May 15, 2005 10:13 am
by FragaGeddon
They probably use one of the veins that go directly to the brain. So it a couple seconds it hits the brain and probably another second for it to take affect on your brain and put you to sleep.
It's probably one of the ways of the brain protecting itself and your body.
But we'll wait to see what the doc says.
Posted: Sun May 15, 2005 10:37 am
by Denz
It's not hard to knock out a person when they're brain dead in the first place.

Posted: Sun May 15, 2005 10:39 am
by saturn
FragaGeddon wrote:They probably use one of the veins that go directly to the brain. So it a couple seconds it hits the brain and probably another second for it to take affect on your brain and put you to sleep.
It's probably one of the ways of the brain protecting itself and your body.
But we'll wait to see what the doc says.
lol you idiot. Veins run to the heart and you never inject anesthestics in an artery.
The anesthestic ran through that vein to your heart (right atrium and ventricle), made a passage through your lungs and back into your heart (left atrium and ventricle). Then it gets pumped through the aorta and splits into many arteries. A portion arrives at the brain where the central narcotic effect takes places.
Splish might have thought that it was 2-3 seconds, but trust me, it's about 30-40 secs before the circulation has brought enough anesthetics to the brain. It probably was some white stuff that they injected and it also burnt a little bit? Then I'm sure that they used Propofol or Etomidate.
Posted: Sun May 15, 2005 10:47 am
by saturn
Those anesthetics vork wery quickly
Posted: Sun May 15, 2005 10:48 am
by Denz
I would like to see the look on the patience face after an injection of H²SO
:icon28:

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Posted: Sun May 15, 2005 10:48 am
by SplishSplash
I didn't see the color, but it did burn a little bit.
Are you sure it takes 30-40 seconds?
Here's why I asked the question in the first place:
Drugs like cocaine for example supposedly have an immidiate effect, and I was wondering how they could get to the brain so fast.
Posted: Sun May 15, 2005 10:48 am
by saturn
you monster!
Posted: Sun May 15, 2005 10:50 am
by Denz
Well it prolly takes 30 seconds to fully pull you under, you feel like it's only a few seconds.
I remember when I was put under. They told me to count backwards from 100, I think I made it to 96
Posted: Sun May 15, 2005 10:55 am
by saturn
SplishSplash wrote:I didn't see the color, but it did burn a little bit.
Are you sure it takes 30-40 seconds?
Here's why I asked the question in the first place:
Drugs like cocaine for example supposedly have an immidiate effect, and I was wondering how they could get to the brain so fast.
It was probably propofol. I've used that a lot with patients undergoing surgery. You inject it slowly since it burns a little bit, you talk softly to the patients for a while and then they're gone quite quickly. See my previous post about how it gets to your brain.
Posted: Sun May 15, 2005 10:57 am
by Denz
Do you make your patients count backwards?
Posted: Sun May 15, 2005 11:01 am
by Denz
What part of the brain does it shut down? or does it "Shut down"? It's like falling asleep without the ability of waking up. So what happens to the brain when this occurs?
Ok Mr. Anesthesiologist, explain.
edit: Grammar Police have arrived.
Posted: Sun May 15, 2005 11:19 am
by FragaGeddon
I was just taking a wild guess.
Posted: Sun May 15, 2005 11:29 am
by saturn
Denz wrote:Do you make your patients count backwards?
nope, I just talk to them slowly and softly about thinking about relaxing things
Denz wrote:What part of the brain does it shut down? or does it "Shut down"? It's like falling asleep without the ability of waking up. So what happens to the brain when this occurs?
Ok Mr. Anesthesiologist, explain.
edit: Grammar Police have arrived.
Depends on the narcotic you use, it's not really a part what you're shutting down. Propofol for example probably has it effects on the GABA-A receptor. A receptor in the brains that's suspectible for Gamma-Amino-Butyric Acid, which is a inhibitory neuro-transmitter.
Most of central working narcotics also lower the brain metabolism.
So people in narcose don't have REM-sleep, since their brains are put to low state.
Posted: Sun May 15, 2005 11:30 am
by saturn
FragaGeddon wrote:I was just taking a wild guess.
luckily you're not a MD :p
Posted: Sun May 15, 2005 11:35 am
by FragaGeddon
I can do heart surgery, just give me a chainsaw.
Posted: Sun May 15, 2005 11:37 am
by Denz
saturn wrote:
So people in narcose don't have REM-sleep, since their brains are put to low state.
That's prolly why drunks when they pass out and wake up, they feel like they never went to sleep.
Posted: Sun May 15, 2005 11:39 am
by Denz
FragaGeddon wrote:I can do heart surgery, just give me a chainsaw.
Is it going to leave a scar?
Posted: Sun May 15, 2005 11:54 am
by FragaGeddon
Denz wrote:FragaGeddon wrote:I can do heart surgery, just give me a chainsaw.
Is it going to leave a scar?
A very, very, very tiny one. You won't even notice it.
Posted: Sun May 15, 2005 11:56 am
by Denz
Ok good, go ahead then but be gentle.
Posted: Sun May 15, 2005 3:08 pm
by Geebs
saturn wrote:Denz wrote:Do you make your patients count backwards?
nope, I just talk to them slowly and softly about thinking about relaxing things
Shit, if you did that to me you'd need to double the dose
Do they do a full induction for dental work? I thought they just went for sedation and then local. In which case it'd be midazolam, which seems to take about 10 seconds.
Then again, as you can tell, I just knock people out for fracture and dislocation reductions, my anaesthetics is pretty damn weak.
Posted: Sun May 15, 2005 3:12 pm
by shadd_.
i had a maxillofacial surgeon pull my wisdom teeth.
