Post what your job is
- GONNAFISTYA
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Freakaloin
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+JuggerNaut+
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46c here todaychopov wrote:Well, it had 40º C today. If you are here on holiday this may be nice but if you have to handle and glue tiny pieces of wood metal and plastic all day it´s quite annoying. Nevertheless I catched a baad sunburn last weekend on the beach... :icon32:+JuggerNaut+ wrote:enviouschopov wrote:I´m an architect. Currently working in southern Spain and atm mostly making a huge model for a project our office is about to build.
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Chupacabra
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+JuggerNaut+
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+JuggerNaut+
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+JuggerNaut+
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tbh, I'm not sure anymore. It's probably the latter one.werldhed wrote:That makes sense. Was the goal to alter the MDCs so they did not activate the donor T cells when exposed to the recipient cells? Would that also reduce the MDC ability to activate T cells when they come in contact with foreign pathogens (e.g. viruses or bacteria). Or where you trying to specifically reduce T cell activation in terms of the Host's antigens and not foreign antigens?saturn wrote: My project was named: "The effects of UVB irradiation on the phenotype and function of murine myeloid dendritic cells".
I derived bone marrow from freshly killed C57Bl/6 mice and cultivated them with GM-CSF to create dendritic cells. Then I irradiated them with variable doses of UVB light (which is known to have a immunosupressive effect). I did a lot of other stuff, but to make it short I tried to alter the T-cell stimulatory effects of dendritic cells so we might create tolerant Th1 and Th2 cells that could be used to fight Graft-versus-Host disease in Leukemia transplant-patients.
If I read my stuff i did 4 years ago, I understand half the stuff was doing back then, haha.
It's easier to remove the T-cells from the bonemarrow transplant, but it has been shown that stemcells and the overall regeneration of the allotransplant (and thus new immune system) will populate the empty bones much quicker with Th1 and Th2 cells allowed in the transplant.
There have been experiment with irradiating the whole donor bonemarrow transplants but that weakened and slowed the whole settling process. That's why I tried an intermediate step of trying to cultivate murine DCs to create tolerant T-cells.
It's great. When some stupid cunt comes in to tell you they've got sunburn (and to get sunburn in England you have to be one hell of a stupid cunt) or hayfever, you can ask them, "okay, is this an accident or an emergency?"saturn wrote:heh, every country has its own name for the ERbusetibi wrote:A&E=accident and emergency?
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+JuggerNaut+
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Keep It Real
Re: Post what your job is
full time stay gucci down stay riding the flyestKn0wFuRy wrote:No one needs to actually name a company or location or how much you make or anything.
Just why not post what your job is? I know we have had these threads before anyone says anything but the last one I read was ages ago so I don't remember your job if you even posted in it.
I will go first.
I am a full time single Mom and I work part time for an agency that provides a social service.
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[xeno]Julios
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